Search on: ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G 
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Descriptor English:   ATP Binding Cassette Transporter, Sub-Family G 
Descriptor Spanish:   Transportador de Casetes de Unión a ATP, Subfamilia G 
Descriptor Portuguese:   Subfamília G de Transportadores de Cassetes de Ligação de ATP 
Synonyms English:   ABCG Proteins
ABCG Transporters
ATP Binding Cassette Transporter, Sub Family G  
Tree Number:   D12.776.157.530.100.228
D12.776.395.550.020.457
D12.776.543.550.192.457
D12.776.543.585.100.228
Definition English:   A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56577 
Unique Identifier:   D000070996 

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